Acute Acalculous Cholecystitis-Associated Bacteremia Has Worse Outcome

Background: Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder without gallstones in setting critical illness. It represents 2%–15% acute (AC) cases. Bacteremia associated with increased morbidity and mortality rates patients intensive care unit (ICU). The incidence bacteremia calculous (ACC) has been described; however, AAC not reported. We hypothesized that have higher rates, leading to worse outcomes than those ACC. Methods: A prospectively collected surgery (ACS) institutional database treated from 2008 through 2018 was queried for having ACC using International Classification Diseases (ICD) 9 10 codes. Demographics, microbiology findings, were extracted. Only positive blood cultures included study. defined two cohorts: bacteremia. Student t-test used continuous variables χ2 Fisher exact tests categorical variables. Multivariable regression applied, statistical significance set at p < 0.05. Results: Of 323 AC, 57 (17.6%) had 266 (82.4%) 19 who a culture, 11 (57.8%) positive. Patients mean age 56.7 ± 15.3 years Body Mass Index (BMI) 26.7 4.9. significantly (n = 6; 10.5% versus n 5; 1.9 %; 0.005), although time between admission diagnosis similar groups (1.2 1.1 0.2 0.5 days; 0.128). younger (53.8 19.2 60.2 8 years; 0.021) longer ICU length stay (LOS) (12.6 7.2 1.3 2.1 0.030). However, there no difference rate 2; 33.3% 1; 20.0%; 1.000). After adjusting age, gender, BMI, Charlson Comorbidity Index, found be independent variable LOS (odds ratio 8.8; 95% confidence interval 1.7–15.9; 0.024). Conclusions: five-fold eight days